서브메뉴
검색
Toward Predictive Control of Fuel-Driven Molecular Motors: Speed and Directional Bias
Toward Predictive Control of Fuel-Driven Molecular Motors: Speed and Directional Bias
상세정보
- 자료유형
- 학위논문 서양
- 최종처리일시
- 20260202103545
- ISBN
- 9798315797791
- DDC
- 541
- 저자명
- Gu, Geyao.
- 서명/저자
- Toward Predictive Control of Fuel-Driven Molecular Motors: Speed and Directional Bias
- 발행사항
- [Sl] : Northwestern University, 2025
- 발행사항
- Ann Arbor : ProQuest Dissertations & Theses, 2025
- 형태사항
- 100 p
- 주기사항
- Source: Dissertations Abstracts International, Volume: 86-12, Section: B.
- 주기사항
- Advisor: Gingrich, Todd.
- 학위논문주기
- Thesis (Ph.D.)--Northwestern University, 2025.
- 초록/해제
- 요약Molecular motors harness chemical energy by coupling to a fuel decomposition reaction and converting it into mechanical work. While biological motors demonstrate high velocity, efficient energy conversion, and near-perfect unidirectionality, the synthetic catalysis-driven motors remain slow and loosely coupled to the fuels. These limitations raise a fundamental question: How can we evaluate and improve the performance of synthetic motors? In my PhD, I explored this through four specific questions: (1) Can structural modification reverse the motor's direction? (2) Can "power stroke" intuition guide design? (3) How precise can fluctuating motors be? (4) Can coupling multiple motors enhance collective speed?These questions are addressed using a nonequilibrium molecular dynamics framework inspired by the first synthetic catalysis-driven catenane motor, enabling direct simulation under steady-state conditions with explicit fuel dynamics.This thesis provides theoretical insight and computational strategies for evaluating and improving synthetic molecular motors. The findings highlight the role of mechanochemical and mechanical coupling, structural designs and manipulation of interactions in guiding motor's performance. While synthetic systems are still in early stages, the principles outlined here provide a foundation for both advancing artificial motors and deepening our understanding of their biological counterparts.
- 일반주제명
- Physical chemistry
- 일반주제명
- Energy
- 일반주제명
- Thermodynamics
- 일반주제명
- Mechanical engineering
- 키워드
- Molecular motors
- 키워드
- Nonequilibrium
- 기타저자
- Northwestern University Chemistry
- 기본자료저록
- Dissertations Abstracts International. 86-12B.
- 전자적 위치 및 접속
- 로그인 후 원문을 볼 수 있습니다.
MARC
008260126s2025 us c eng d■001000017357678
■00520260202103545
■006m o d
■007cr#unu||||||||
■020 ▼a9798315797791
■035 ▼a(MiAaPQ)AAI32041250
■040 ▼aMiAaPQ▼cMiAaPQ
■0820 ▼a541
■1001 ▼aGu, Geyao.▼0(orcid)0000-0002-4266-4716
■24510▼aToward Predictive Control of Fuel-Driven Molecular Motors: Speed and Directional Bias
■260 ▼a[Sl]▼bNorthwestern University▼c2025
■260 1▼aAnn Arbor▼bProQuest Dissertations & Theses▼c2025
■300 ▼a100 p
■500 ▼aSource: Dissertations Abstracts International, Volume: 86-12, Section: B.
■500 ▼aAdvisor: Gingrich, Todd.
■5021 ▼aThesis (Ph.D.)--Northwestern University, 2025.
■520 ▼aMolecular motors harness chemical energy by coupling to a fuel decomposition reaction and converting it into mechanical work. While biological motors demonstrate high velocity, efficient energy conversion, and near-perfect unidirectionality, the synthetic catalysis-driven motors remain slow and loosely coupled to the fuels. These limitations raise a fundamental question: How can we evaluate and improve the performance of synthetic motors? In my PhD, I explored this through four specific questions: (1) Can structural modification reverse the motor's direction? (2) Can "power stroke" intuition guide design? (3) How precise can fluctuating motors be? (4) Can coupling multiple motors enhance collective speed?These questions are addressed using a nonequilibrium molecular dynamics framework inspired by the first synthetic catalysis-driven catenane motor, enabling direct simulation under steady-state conditions with explicit fuel dynamics.This thesis provides theoretical insight and computational strategies for evaluating and improving synthetic molecular motors. The findings highlight the role of mechanochemical and mechanical coupling, structural designs and manipulation of interactions in guiding motor's performance. While synthetic systems are still in early stages, the principles outlined here provide a foundation for both advancing artificial motors and deepening our understanding of their biological counterparts.
■590 ▼aSchool code: 0163.
■650 4▼aPhysical chemistry
■650 4▼aEnergy
■650 4▼aThermodynamics
■650 4▼aMechanical engineering
■653 ▼aCatalysis-driven motors
■653 ▼aMechanical coupling
■653 ▼aMechanochemical coupling
■653 ▼aMolecular motors
■653 ▼aNonequilibrium
■690 ▼a0494
■690 ▼a0548
■690 ▼a0348
■690 ▼a0791
■71020▼aNorthwestern University▼bChemistry.
■7730 ▼tDissertations Abstracts International▼g86-12B.
■790 ▼a0163
■791 ▼aPh.D.
■792 ▼a2025
■793 ▼aEnglish
■85640▼uhttp://www.riss.kr/pdu/ddodLink.do?id=T17357678▼nKERIS▼z이 자료의 원문은 한국교육학술정보원에서 제공합니다.
