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Efficient Parallel Computation of Particle-Based Biological Systems: Applications to Simulations of Bird Flocks and Optimizing Models of Cardiac Tissue
Efficient Parallel Computation of Particle-Based Biological Systems: Applications to Simul...
Efficient Parallel Computation of Particle-Based Biological Systems: Applications to Simulations of Bird Flocks and Optimizing Models of Cardiac Tissue

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자료유형  
 학위논문 서양
최종처리일시  
20260202105503
ISBN  
9798263324902
DDC  
001
저자명  
Comstock, Maxfield Roth.
서명/저자  
Efficient Parallel Computation of Particle-Based Biological Systems: Applications to Simulations of Bird Flocks and Optimizing Models of Cardiac Tissue
발행사항  
[Sl] : Georgia Institute of Technology, 2025
발행사항  
Ann Arbor : ProQuest Dissertations & Theses, 2025
형태사항  
185 p
주기사항  
Source: Dissertations Abstracts International, Volume: 87-06, Section: B.
주기사항  
Advisor: Cherry, Elizabeth.
학위논문주기  
Thesis (Ph.D.)--Georgia Institute of Technology, 2025.
초록/해제  
요약Graphics processing units (GPUs) are ubiquitous in modern computers, and are characterized by their large-scale parallel computing capability. Many computing problems that require updating state variables for a large number of mostly independent agents are well-suited to simulation using GPUs, as the steps that can be parallelized often represent the majority of the computation but are individually simple. This thesis focuses on two particle-based systems which have been implemented using this approach. In both cases, these simulations use the Web Graphics Library (WebGL) available in all modern web browsers to utilize any available graphics hardware without requiring any manual software installation, configuration, or compilation by the end-user. The first program uses particle swarm optimization (PSO), an optimization technique inspired by the behavior of groups of animals, to identify parameterizations of cardiac models to match experimental data. This tool, called CardioFit, allows the identification of parameters in a matter of seconds on most computers and is capable of finding low-error solutions even for challenging datasets, such as data recorded from human hearts exhibiting Brugada syndrome. By design, CardioFit is easy to use through a user interface without requiring any code to be written or modified by the end-user, while still allowing control over optimization parameters for advanced users. The second program simulates flocks of up to tens of thousands of birds in near-real time, with interactive settings to choose between a variety of flocking models, change their parameters, and observe the behavior through a live visualization. This flocking simulation reveals that large flocks of birds place greater constraints on existing flocking models to obtain desired behaviors such as the ability to maintain the flock through turns due to the need for long-range information transfer.
일반주제명  
Software
일반주제명  
Physiology
일반주제명  
Computer science
키워드  
Graphics processing units
키워드  
Particle swarm optimization
기타저자  
Georgia Institute of Technology.
기본자료저록  
Dissertations Abstracts International. 87-06B.
전자적 위치 및 접속  
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■020    ▼a9798263324902
■035    ▼a(MiAaPQ)AAI32307954
■035    ▼a(MiAaPQ)GeorgiaTech78722
■040    ▼aMiAaPQ▼cMiAaPQ
■0820  ▼a001
■1001  ▼aComstock,  Maxfield  Roth.
■24510▼aEfficient  Parallel  Computation  of  Particle-Based  Biological  Systems:  Applications  to  Simulations  of  Bird  Flocks  and  Optimizing  Models  of  Cardiac  Tissue
■260    ▼a[Sl]▼bGeorgia  Institute  of  Technology▼c2025
■260  1▼aAnn  Arbor▼bProQuest  Dissertations  &  Theses▼c2025
■300    ▼a185  p
■500    ▼aSource:  Dissertations  Abstracts  International,  Volume:  87-06,  Section:  B.
■500    ▼aAdvisor:  Cherry,  Elizabeth.
■5021  ▼aThesis  (Ph.D.)--Georgia  Institute  of  Technology,  2025.
■520    ▼aGraphics  processing  units  (GPUs)  are  ubiquitous  in  modern  computers,  and  are  characterized  by  their  large-scale  parallel  computing  capability.  Many  computing  problems  that  require  updating  state  variables  for  a  large  number  of  mostly  independent  agents  are  well-suited  to  simulation  using  GPUs,  as  the  steps  that  can  be  parallelized  often  represent  the  majority  of  the  computation  but  are  individually  simple.  This  thesis  focuses  on  two  particle-based  systems  which  have  been  implemented  using  this  approach.  In  both  cases,  these  simulations  use  the  Web  Graphics  Library  (WebGL)  available  in  all  modern  web  browsers  to  utilize  any  available  graphics  hardware  without  requiring  any  manual  software  installation,  configuration,  or  compilation  by  the  end-user.  The  first  program  uses  particle  swarm  optimization  (PSO),  an  optimization  technique  inspired  by  the  behavior  of  groups  of  animals,  to  identify  parameterizations  of  cardiac  models  to  match  experimental  data.  This  tool,  called  CardioFit,  allows  the  identification  of  parameters  in  a  matter  of  seconds  on  most  computers  and  is  capable  of  finding  low-error  solutions  even  for  challenging  datasets,  such  as  data  recorded  from  human  hearts  exhibiting  Brugada  syndrome.  By  design,  CardioFit  is  easy  to  use  through  a  user  interface  without  requiring  any  code  to  be  written  or  modified  by  the  end-user,  while  still  allowing  control  over  optimization  parameters  for  advanced  users.  The  second  program  simulates  flocks  of  up  to  tens  of  thousands  of  birds  in  near-real  time,  with  interactive  settings  to  choose  between  a  variety  of  flocking  models,  change  their  parameters,  and  observe  the  behavior  through  a  live  visualization.  This  flocking  simulation  reveals  that  large  flocks  of  birds  place  greater  constraints  on  existing  flocking  models  to  obtain  desired  behaviors  such  as  the  ability  to  maintain  the  flock  through  turns  due  to  the  need  for  long-range  information  transfer.
■590    ▼aSchool  code:  0078.
■650  4▼aSoftware
■650  4▼aPhysiology
■650  4▼aComputer  science
■653    ▼aGraphics  processing  units
■653    ▼aParticle  swarm  optimization
■690    ▼a0984
■690    ▼a0719
■71020▼aGeorgia  Institute  of  Technology.
■7730  ▼tDissertations  Abstracts  International▼g87-06B.
■790    ▼a0078
■791    ▼aPh.D.
■792    ▼a2025
■793    ▼aEnglish
■85640▼uhttp://www.riss.kr/pdu/ddodLink.do?id=T17360297▼nKERIS▼z이  자료의  원문은  한국교육학술정보원에서  제공합니다.

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