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AI-Driven Speech Neuroprostheses for Restoring Naturalistic Communication and Embodiment
AI-Driven Speech Neuroprostheses for Restoring Naturalistic Communication and Embodiment
AI-Driven Speech Neuroprostheses for Restoring Naturalistic Communication and Embodiment

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자료유형  
 학위논문 서양
최종처리일시  
20260202104843
ISBN  
9798293892686
DDC  
616
저자명  
Littlejohn, Kaylo.
서명/저자  
AI-Driven Speech Neuroprostheses for Restoring Naturalistic Communication and Embodiment
발행사항  
[Sl] : University of California, Berkeley, 2025
발행사항  
Ann Arbor : ProQuest Dissertations & Theses, 2025
형태사항  
107 p
주기사항  
Source: Dissertations Abstracts International, Volume: 87-04, Section: B.
주기사항  
Advisor: Anumanchipalli, Gopala;Chang, Edward.
학위논문주기  
Thesis (Ph.D.)--University of California, Berkeley, 2025.
초록/해제  
요약Can we rebuild the bridge between brain and voice, restoring human communication for people with paralysis? This thesis outlines our translational systems that restore speech to individuals with vocal-tract paralysis.Speech neuroprostheses have the potential to restore communication and embodiment to individuals living with paralysis, but achieving naturalistic speed and expressivity has remained elusive. The advances presented in this thesis enabled a clinical trial participant with severe limb and vocal paralysis to "speak again" for the first time in 18+ years using an AI "brain-to-voice" decoder that restores their pre-injury voice. We use high-density surface recordings of the speech cortex in a participant to achieve high-performance, large-vocabulary, real-time decoding across three complementary speech-related output modalities: text, speech audio, and facial-avatar animation. Leveraging advances in machine learning for automatic speech recognition and synthesis, we trained and evaluated deep-learning models using neural data collected as participants attempted to silently speak a sentence, enabling decoding speeds approaching natural conversational rates. We also demonstrate the control of virtual orofacial movements for speech and non-speech communicative gestures via a high-fidelity "digital talking avatar" controlled by the participant's brain.Building on the above advances in high-performance brain-to-speech decoding, I outline our findings demonstrating low-latency, continuously streaming brain-to-voice synthesis with neural decoding in 80-ms increments. The recurrent neural network transducer models demonstrated implicit speech detection capabilities and could continuously decode speech indefinitely, enabling uninterrupted use of the decoder and further increasing speed. Our framework also successfully generalized to other silent-speech interfaces, including single-unit recordings and electromyography.Together, the findings in this thesis introduce a multimodal, low-latency speech-neuroprosthetic approach with substantial promise for restoring full, embodied communication to people with severe paralysis. A video overview of our brain decoding technique and impact can be found at this link.
일반주제명  
Neurosciences
일반주제명  
Health sciences
키워드  
Brain-to-speech decoding
키워드  
Machine learning
키워드  
Automatic speech recognition
기타저자  
University of California, Berkeley Electrical Engineering & Computer Sciences
기본자료저록  
Dissertations Abstracts International. 87-04B.
전자적 위치 및 접속  
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MARC

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■040    ▼aMiAaPQ▼cMiAaPQ
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■1001  ▼aLittlejohn,  Kaylo.
■24510▼aAI-Driven  Speech  Neuroprostheses  for  Restoring  Naturalistic  Communication  and  Embodiment
■260    ▼a[Sl]▼bUniversity  of  California,  Berkeley▼c2025
■260  1▼aAnn  Arbor▼bProQuest  Dissertations  &  Theses▼c2025
■300    ▼a107  p
■500    ▼aSource:  Dissertations  Abstracts  International,  Volume:  87-04,  Section:  B.
■500    ▼aAdvisor:  Anumanchipalli,  Gopala;Chang,  Edward.
■5021  ▼aThesis  (Ph.D.)--University  of  California,  Berkeley,  2025.
■520    ▼aCan  we  rebuild  the  bridge  between  brain  and  voice,  restoring  human  communication  for  people  with  paralysis?  This  thesis  outlines  our  translational  systems  that  restore  speech  to  individuals  with  vocal-tract  paralysis.Speech  neuroprostheses  have  the  potential  to  restore  communication  and  embodiment  to  individuals  living  with  paralysis,  but  achieving  naturalistic  speed  and  expressivity  has  remained  elusive.  The  advances  presented  in  this  thesis  enabled  a  clinical  trial  participant  with  severe  limb  and  vocal  paralysis  to  "speak  again"  for  the  first  time  in  18+  years  using  an  AI  "brain-to-voice"  decoder  that  restores  their  pre-injury  voice.  We  use  high-density  surface  recordings  of  the  speech  cortex  in  a  participant  to  achieve  high-performance,  large-vocabulary,  real-time  decoding  across  three  complementary  speech-related  output  modalities:  text,  speech  audio,  and  facial-avatar  animation.  Leveraging  advances  in  machine  learning  for  automatic  speech  recognition  and  synthesis,  we  trained  and  evaluated  deep-learning  models  using  neural  data  collected  as  participants  attempted  to  silently  speak  a  sentence,  enabling  decoding  speeds  approaching  natural  conversational  rates.  We  also  demonstrate  the  control  of  virtual  orofacial  movements  for  speech  and  non-speech  communicative  gestures  via  a  high-fidelity  "digital  talking  avatar"  controlled  by  the  participant's  brain.Building  on  the  above  advances  in  high-performance  brain-to-speech  decoding,  I  outline  our  findings  demonstrating  low-latency,  continuously  streaming  brain-to-voice  synthesis  with  neural  decoding  in  80-ms  increments.  The  recurrent  neural  network  transducer  models  demonstrated  implicit  speech  detection  capabilities  and  could  continuously  decode  speech  indefinitely,  enabling  uninterrupted  use  of  the  decoder  and  further  increasing  speed.  Our  framework  also  successfully  generalized  to  other  silent-speech  interfaces,  including  single-unit  recordings  and  electromyography.Together,  the  findings  in  this  thesis  introduce  a  multimodal,  low-latency  speech-neuroprosthetic  approach  with  substantial  promise  for  restoring  full,  embodied  communication  to  people  with  severe  paralysis. A  video  overview  of  our  brain  decoding  technique  and  impact  can  be  found  at  this  link.
■590    ▼aSchool  code:  0028.
■650  4▼aNeurosciences
■650  4▼aHealth  sciences
■653    ▼aBrain-to-speech  decoding
■653    ▼aMachine  learning
■653    ▼aAutomatic  speech  recognition
■690    ▼a0800
■690    ▼a0566
■690    ▼a0317
■71020▼aUniversity  of  California,  Berkeley▼bElectrical  Engineering  &  Computer  Sciences.
■7730  ▼tDissertations  Abstracts  International▼g87-04B.
■790    ▼a0028
■791    ▼aPh.D.
■792    ▼a2025
■793    ▼aEnglish
■85640▼uhttp://www.riss.kr/pdu/ddodLink.do?id=T17359160▼nKERIS▼z이  자료의  원문은  한국교육학술정보원에서  제공합니다.

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