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Machine Learning-Assisted Treatment Selection for Smoking Cessation
Machine Learning-Assisted Treatment Selection for Smoking Cessation
Machine Learning-Assisted Treatment Selection for Smoking Cessation

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자료유형  
 학위논문 서양
최종처리일시  
20260202104845
ISBN  
9798290939889
DDC  
157
저자명  
Fronk, Gaylen E.
서명/저자  
Machine Learning-Assisted Treatment Selection for Smoking Cessation
발행사항  
[Sl] : The University of Wisconsin - Madison, 2025
발행사항  
Ann Arbor : ProQuest Dissertations & Theses, 2025
형태사항  
104 p
주기사항  
Source: Dissertations Abstracts International, Volume: 87-02, Section: B.
주기사항  
Advisor: Curtin, John J.
학위논문주기  
Thesis (Ph.D.)--The University of Wisconsin - Madison, 2025.
초록/해제  
요약Precision mental health seeks to select the right treatment for a patient given personal characteristics. The purpose of this project was to build a machine learning model that could select among first-line medication treatments for cigarette smoking. We used data from a previously completed comparative effectiveness trial in which participants were richly characterized at baseline before being randomly assigned to varenicline, combination nicotine replacement therapy, or nicotine patch. We built a model predicting treatment success (abstinent vs. smoking) using baseline characteristics and their interactions with treatment. Models were fit, selected, and evaluated using nested cross-validation and the performance metric area under the receiving operator characteristic curve (auROC). Our best models had a median auROC of 0.69 in held-out test sets. We used this model to calculate probabilities of smoking cessation success for each participant on each of the three treatments to identify their model-predicted best treatment. Individuals who received their model-predicted best treatment during the original trial were more likely to quit successfully than individuals who did not (OR = 1.851, p = 0.004). This project produces a clinically implementable treatment selection model to assist people quitting cigarette smoking.
일반주제명  
Clinical psychology
일반주제명  
Psychology
일반주제명  
Mental health
키워드  
Machine learning
키워드  
Precision medicine
키워드  
Smoking cessation
키워드  
Treatment selection
키워드  
Medication treatments
기타저자  
The University of Wisconsin - Madison Psychology
기본자료저록  
Dissertations Abstracts International. 87-02B.
전자적 위치 및 접속  
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MARC

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■040    ▼aMiAaPQ▼cMiAaPQ
■0820  ▼a157
■1001  ▼aFronk,  Gaylen  E.
■24510▼aMachine  Learning-Assisted  Treatment  Selection  for  Smoking  Cessation
■260    ▼a[Sl]▼bThe  University  of  Wisconsin  -  Madison▼c2025
■260  1▼aAnn  Arbor▼bProQuest  Dissertations  &  Theses▼c2025
■300    ▼a104  p
■500    ▼aSource:  Dissertations  Abstracts  International,  Volume:  87-02,  Section:  B.
■500    ▼aAdvisor:  Curtin,  John  J.
■5021  ▼aThesis  (Ph.D.)--The  University  of  Wisconsin  -  Madison,  2025.
■520    ▼aPrecision  mental  health  seeks  to  select  the  right  treatment  for  a  patient  given  personal  characteristics.  The  purpose  of  this  project  was  to  build  a  machine  learning  model  that  could  select  among  first-line  medication  treatments  for  cigarette  smoking.  We  used  data  from  a  previously  completed  comparative  effectiveness  trial  in  which  participants  were  richly  characterized  at  baseline  before  being  randomly  assigned  to  varenicline,  combination  nicotine  replacement  therapy,  or  nicotine  patch.  We  built  a  model  predicting  treatment  success  (abstinent  vs.  smoking)  using  baseline  characteristics  and  their  interactions  with  treatment.  Models  were  fit,  selected,  and  evaluated  using  nested  cross-validation  and  the  performance  metric  area  under  the  receiving  operator  characteristic  curve  (auROC).  Our  best  models  had  a  median  auROC  of  0.69  in  held-out  test  sets.  We  used  this  model  to  calculate  probabilities  of  smoking  cessation  success  for  each  participant  on  each  of  the  three  treatments  to  identify  their  model-predicted  best  treatment.  Individuals  who  received  their  model-predicted  best  treatment  during  the  original  trial  were  more  likely  to  quit  successfully  than  individuals  who  did  not  (OR  =  1.851,  p  =  0.004).  This  project  produces  a  clinically  implementable  treatment  selection  model  to  assist  people  quitting  cigarette  smoking.
■590    ▼aSchool  code:  0262.
■650  4▼aClinical  psychology
■650  4▼aPsychology
■650  4▼aMental  health
■653    ▼aMachine  learning
■653    ▼aPrecision  medicine
■653    ▼aSmoking  cessation
■653    ▼aTreatment  selection
■653    ▼aMedication  treatments
■690    ▼a0622
■690    ▼a0621
■690    ▼a0347
■71020▼aThe  University  of  Wisconsin  -  Madison▼bPsychology.
■7730  ▼tDissertations  Abstracts  International▼g87-02B.
■790    ▼a0262
■791    ▼aPh.D.
■792    ▼a2025
■793    ▼aEnglish
■85640▼uhttp://www.riss.kr/pdu/ddodLink.do?id=T17359173▼nKERIS▼z이  자료의  원문은  한국교육학술정보원에서  제공합니다.

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