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Development and Applications of Cluster-Based Motion Resolved Technique for Cardiac Cine MRI in Complex Arrhythmias
Development and Applications of Cluster-Based Motion Resolved Technique for Cardiac Cine MRI in Complex Arrhythmias
상세정보
- 자료유형
- 학위논문 서양
- 최종처리일시
- 20260202104845
- ISBN
- 9798290943862
- DDC
- 616
- 저자명
- Ming, Zhengyang.
- 서명/저자
- Development and Applications of Cluster-Based Motion Resolved Technique for Cardiac Cine MRI in Complex Arrhythmias
- 발행사항
- [Sl] : University of California, Los Angeles, 2025
- 발행사항
- Ann Arbor : ProQuest Dissertations & Theses, 2025
- 형태사항
- 166 p
- 주기사항
- Source: Dissertations Abstracts International, Volume: 87-02, Section: B.
- 주기사항
- Advisor: Nguyen, Kim-Lien;Christodoulou, Anthony G.
- 학위논문주기
- Thesis (Ph.D.)--University of California, Los Angeles, 2025.
- 초록/해제
- 요약Magnetic resonance imaging (MRI) is prone to image blurring and artifacts due to motion, particularly in cardiac imaging. Electrocardiogram (ECG) gating was developed to compensate for cardiac motion during breath-holding and is effective for patients with sinus rhythm. For patients with irregular heart rhythms, arrhythmia rejection is used to filter out abnormal heartbeats, allowing ECG gating to operate on normal beats. However, when a high percentage of heartbeats are abnormal, this method can significantly prolong scan times, complicating the detection of actual cardiac motion. Recent studies have attempted to classify heartbeats into distinct types for specific reconstructions; however, these methods are only applicable to arrhythmias with defined patterns and lack effectiveness for highly irregular conditions, such as atrial fibrillation. Additionally, ECG-based techniques can be affected by noise and instability, particularly in high magnetic fields, while non-ECG-based methods usually assume periodic cardiac motion and are seldom tested on patients in atrial fibrillation. To address the challenges of motion in cardiac imaging for arrhythmia patients, this dissertation focuses on developing motion-resolving techniques for complex arrhythmias such as atrial fibrillation. The first objective is to establish a basic clustering method to demonstrate its effectiveness in managing motion in sinus rhythm and selected arrhythmia cases. The second objective involves customizing the clustering algorithm to enhance image quality and performance in the presence of highly irregular cardiac motion. The final objective examines the robustness of the adaptive clustering approach under various combinations of regular and irregular cardiac and respiratory motion, highlighting its potential for clinical use. This dissertation significantly advances our approach to resolving irregular motion in cardiac imaging and enhances the detection of arrhythmia dynamics. It also presents a universal clustering-based framework for addressing motion challenges in cardiac MRI.
- 일반주제명
- Medical imaging
- 일반주제명
- Biomedical engineering
- 일반주제명
- Health sciences
- 키워드
- Cardiac motion
- 기타저자
- University of California, Los Angeles Physics and Biology in Medicine 009Y
- 기본자료저록
- Dissertations Abstracts International. 87-02B.
- 전자적 위치 및 접속
- 로그인 후 원문을 볼 수 있습니다.
MARC
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■020 ▼a9798290943862
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■040 ▼aMiAaPQ▼cMiAaPQ
■0820 ▼a616
■1001 ▼aMing, Zhengyang.
■24510▼aDevelopment and Applications of Cluster-Based Motion Resolved Technique for Cardiac Cine MRI in Complex Arrhythmias
■260 ▼a[Sl]▼bUniversity of California, Los Angeles▼c2025
■260 1▼aAnn Arbor▼bProQuest Dissertations & Theses▼c2025
■300 ▼a166 p
■500 ▼aSource: Dissertations Abstracts International, Volume: 87-02, Section: B.
■500 ▼aAdvisor: Nguyen, Kim-Lien;Christodoulou, Anthony G.
■5021 ▼aThesis (Ph.D.)--University of California, Los Angeles, 2025.
■520 ▼aMagnetic resonance imaging (MRI) is prone to image blurring and artifacts due to motion, particularly in cardiac imaging. Electrocardiogram (ECG) gating was developed to compensate for cardiac motion during breath-holding and is effective for patients with sinus rhythm. For patients with irregular heart rhythms, arrhythmia rejection is used to filter out abnormal heartbeats, allowing ECG gating to operate on normal beats. However, when a high percentage of heartbeats are abnormal, this method can significantly prolong scan times, complicating the detection of actual cardiac motion. Recent studies have attempted to classify heartbeats into distinct types for specific reconstructions; however, these methods are only applicable to arrhythmias with defined patterns and lack effectiveness for highly irregular conditions, such as atrial fibrillation. Additionally, ECG-based techniques can be affected by noise and instability, particularly in high magnetic fields, while non-ECG-based methods usually assume periodic cardiac motion and are seldom tested on patients in atrial fibrillation. To address the challenges of motion in cardiac imaging for arrhythmia patients, this dissertation focuses on developing motion-resolving techniques for complex arrhythmias such as atrial fibrillation. The first objective is to establish a basic clustering method to demonstrate its effectiveness in managing motion in sinus rhythm and selected arrhythmia cases. The second objective involves customizing the clustering algorithm to enhance image quality and performance in the presence of highly irregular cardiac motion. The final objective examines the robustness of the adaptive clustering approach under various combinations of regular and irregular cardiac and respiratory motion, highlighting its potential for clinical use. This dissertation significantly advances our approach to resolving irregular motion in cardiac imaging and enhances the detection of arrhythmia dynamics. It also presents a universal clustering-based framework for addressing motion challenges in cardiac MRI.
■590 ▼aSchool code: 0031.
■650 4▼aMedical imaging
■650 4▼aBiomedical engineering
■650 4▼aHealth sciences
■653 ▼aAtrial fibrillation
■653 ▼aCardiac cine imaging
■653 ▼aCardiac motion
■653 ▼aClustering algorithm
■653 ▼aMagnetic resonance imaging
■690 ▼a0574
■690 ▼a0541
■690 ▼a0566
■690 ▼a0769
■71020▼aUniversity of California, Los Angeles▼bPhysics and Biology in Medicine 009Y.
■7730 ▼tDissertations Abstracts International▼g87-02B.
■790 ▼a0031
■791 ▼aPh.D.
■792 ▼a2025
■793 ▼aEnglish
■85640▼uhttp://www.riss.kr/pdu/ddodLink.do?id=T17359179▼nKERIS▼z이 자료의 원문은 한국교육학술정보원에서 제공합니다.


