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Building a Foundation for One-Health Centric Tickborne Pathogen Research
Building a Foundation for One-Health Centric Tickborne Pathogen Research
Building a Foundation for One-Health Centric Tickborne Pathogen Research

상세정보

자료유형  
 학위논문 서양
최종처리일시  
20260202105154
ISBN  
9798297648906
DDC  
614
저자명  
Khoo, Benedict Sean Lay Chee.
서명/저자  
Building a Foundation for One-Health Centric Tickborne Pathogen Research
발행사항  
[Sl] : University of Minnesota, 2025
발행사항  
Ann Arbor : ProQuest Dissertations & Theses, 2025
형태사항  
101 p
주기사항  
Source: Dissertations Abstracts International, Volume: 87-04, Section: B.
주기사항  
Advisor: Oliver, Jonathan.
학위논문주기  
Thesis (Ph.D.)--University of Minnesota, 2025.
초록/해제  
요약Tickborne diseases represent the largest share of vector-borne disease by case numbers in the United States and are set to only grow with the changing climate and environment. The primary vector for most of the tickborne diseases in the US is Ixodes scapularis, being responsible for Lyme disease, leading cause of vector-borne related morbidity in the US. However, the field of tickborne diseases in public health has often focused mainly on the human health aspect and as such interventions and treatments are focused solely on one facet of the endemic cycle that is characteristic of any vector-borne disease cycle. This highlights the importance of continued research into the field of tickborne disease. To truly understand tickborne diseases, we must approach this problem with a One-Health framework and look at not just the human health aspects but also focus on the vectors involved, the wildlife hosts and the pathogens and other microbes that may have a role in this. This dissertation aims to help build tools and a foundation to aid in future research focused on the tick, their wildlife hosts and the pathogens involved. Aim 1's goal is to address the gaps in literature on tick surveillance for non-nymphal life stages which are not of direct human health concern. Aim 2 seeks to utilize the data collected in Aim 1 and from the literature to identify important hosts or timepoints in a tickborne pathogen's endemic circulation. While Aim 3 seeks to develop tools to aid in future research of tick-pathogen interactions studies and possibly open novel control avenues to help control the levels of tick or tickborne pathogens in the wild.
일반주제명  
Public health
일반주제명  
Microbiology
일반주제명  
Cellular biology
일반주제명  
Health sciences
일반주제명  
Parasitology
키워드  
Ixodes scapularis
키워드  
One-health
키워드  
Public health surveillance
키워드  
Tickborne diseases
키워드  
Vector-borne disease
기타저자  
University of Minnesota Environmental Health
기본자료저록  
Dissertations Abstracts International. 87-04B.
전자적 위치 및 접속  
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■035    ▼a(MiAaPQ)AAI32242885
■040    ▼aMiAaPQ▼cMiAaPQ
■0820  ▼a614
■1001  ▼aKhoo,  Benedict  Sean  Lay  Chee.
■24510▼aBuilding  a  Foundation  for  One-Health  Centric  Tickborne  Pathogen  Research
■260    ▼a[Sl]▼bUniversity  of  Minnesota▼c2025
■260  1▼aAnn  Arbor▼bProQuest  Dissertations  &  Theses▼c2025
■300    ▼a101  p
■500    ▼aSource:  Dissertations  Abstracts  International,  Volume:  87-04,  Section:  B.
■500    ▼aAdvisor:  Oliver,  Jonathan.
■5021  ▼aThesis  (Ph.D.)--University  of  Minnesota,  2025.
■520    ▼aTickborne  diseases  represent  the  largest  share  of  vector-borne  disease  by  case  numbers  in  the  United  States  and  are  set  to  only  grow  with  the  changing  climate  and  environment.  The  primary  vector  for  most  of  the  tickborne  diseases  in  the  US  is  Ixodes  scapularis,  being  responsible  for  Lyme  disease,  leading  cause  of  vector-borne  related  morbidity  in  the  US.  However,  the  field  of  tickborne  diseases  in  public  health  has  often  focused  mainly  on  the  human  health  aspect  and  as  such  interventions  and  treatments  are  focused  solely  on  one  facet  of  the  endemic  cycle  that  is  characteristic  of  any  vector-borne  disease  cycle.  This  highlights  the  importance  of  continued  research  into  the  field  of  tickborne  disease.  To  truly  understand  tickborne  diseases,  we  must  approach  this  problem  with  a  One-Health  framework  and  look  at  not  just  the  human  health  aspects  but  also  focus  on  the  vectors  involved,  the  wildlife  hosts  and  the  pathogens  and  other  microbes  that  may  have  a  role  in  this.  This  dissertation  aims  to  help  build  tools  and  a  foundation  to  aid  in  future  research  focused  on  the  tick,  their  wildlife  hosts  and  the  pathogens  involved.  Aim  1's  goal  is  to  address  the  gaps  in  literature  on  tick  surveillance  for  non-nymphal  life  stages  which  are  not  of  direct  human  health  concern.  Aim  2  seeks  to  utilize  the  data  collected  in  Aim  1  and  from  the  literature  to  identify  important  hosts  or  timepoints  in  a  tickborne  pathogen's  endemic  circulation.  While  Aim  3  seeks  to  develop  tools  to  aid  in  future  research  of  tick-pathogen  interactions  studies  and  possibly  open  novel  control  avenues  to  help  control  the  levels  of  tick  or  tickborne  pathogens  in  the  wild.
■590    ▼aSchool  code:  0130.
■650  4▼aPublic  health
■650  4▼aMicrobiology
■650  4▼aCellular  biology
■650  4▼aHealth  sciences
■650  4▼aParasitology
■653    ▼aIxodes  scapularis
■653    ▼aOne-health
■653    ▼aPublic  health  surveillance
■653    ▼aTickborne  diseases
■653    ▼aVector-borne  disease
■690    ▼a0573
■690    ▼a0379
■690    ▼a0566
■690    ▼a0410
■690    ▼a0718
■71020▼aUniversity  of  Minnesota▼bEnvironmental  Health.
■7730  ▼tDissertations  Abstracts  International▼g87-04B.
■790    ▼a0130
■791    ▼aPh.D.
■792    ▼a2025
■793    ▼aEnglish
■85640▼uhttp://www.riss.kr/pdu/ddodLink.do?id=T17359663▼nKERIS▼z이  자료의  원문은  한국교육학술정보원에서  제공합니다.

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