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Identifying and Understanding Microtubule Associated Proteins
Identifying and Understanding Microtubule Associated Proteins
Identifying and Understanding Microtubule Associated Proteins

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자료유형  
 학위논문 서양
최종처리일시  
20260202104740
ISBN  
9798290649832
DDC  
612
저자명  
Tran, Michael Viet.
서명/저자  
Identifying and Understanding Microtubule Associated Proteins
발행사항  
[Sl] : Stanford University, 2023
발행사항  
Ann Arbor : ProQuest Dissertations & Theses, 2023
형태사항  
135 p
주기사항  
Source: Dissertations Abstracts International, Volume: 87-01, Section: B.
주기사항  
Advisor: Feldman, Jessica.
학위논문주기  
Thesis (Ph.D.)--Stanford University, 2023.
초록/해제  
요약Microtubules are intracellular polymers that are necessary for various essential processes ranging from cell division to maintaining cell structure. However, microtubules must adopt specific patterns in many of these processes even though the polymers are built using the same subunit. To achieve this range of patterns, microtubule associated proteins (MAPs) modulate microtubules by performing functions like nucleation and crosslinking. While the localization and function of many MAPs are known, we still do not understand how most microtubule patterns are achieved nor the role of MAPs in this patterning. In this study we used C. elegansas a model to find that the understudied MAP9 has a conserved and specific localization to microtubule doublets.
일반주제명  
Physiology
일반주제명  
Neurons
일반주제명  
Worms
일반주제명  
Microscopy
일반주제명  
Cell division
기타저자  
Stanford University.
기본자료저록  
Dissertations Abstracts International. 87-01B.
전자적 위치 및 접속  
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MARC

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■1001  ▼aTran,  Michael  Viet.
■24510▼aIdentifying  and  Understanding  Microtubule  Associated  Proteins
■260    ▼a[Sl]▼bStanford  University▼c2023
■260  1▼aAnn  Arbor▼bProQuest  Dissertations  &  Theses▼c2023
■300    ▼a135  p
■500    ▼aSource:  Dissertations  Abstracts  International,  Volume:  87-01,  Section:  B.
■500    ▼aAdvisor:  Feldman,  Jessica.
■5021  ▼aThesis  (Ph.D.)--Stanford  University,  2023.
■520    ▼aMicrotubules  are  intracellular  polymers  that  are  necessary  for  various  essential  processes  ranging  from  cell  division  to  maintaining  cell  structure.  However,  microtubules  must  adopt  specific  patterns  in  many  of  these  processes  even  though  the  polymers  are  built  using  the  same  subunit.  To  achieve  this  range  of  patterns,  microtubule  associated  proteins  (MAPs)  modulate  microtubules  by  performing  functions  like  nucleation  and  crosslinking.  While  the  localization  and  function  of  many  MAPs  are  known,  we  still  do  not  understand  how  most  microtubule  patterns  are  achieved  nor  the  role  of  MAPs  in  this  patterning.  In  this  study  we  used  C.  elegansas  a  model  to  find  that  the  understudied  MAP9  has  a  conserved  and  specific  localization  to  microtubule  doublets.
■590    ▼aSchool  code:  0212.
■650  4▼aPhysiology
■650  4▼aNeurons
■650  4▼aWorms
■650  4▼aMicroscopy
■650  4▼aCell  division
■690    ▼a0719
■71020▼aStanford  University.
■7730  ▼tDissertations  Abstracts  International▼g87-01B.
■790    ▼a0212
■791    ▼aPh.D.
■792    ▼a2023
■793    ▼aEnglish
■85640▼uhttp://www.riss.kr/pdu/ddodLink.do?id=T17358707▼nKERIS▼z이  자료의  원문은  한국교육학술정보원에서  제공합니다.

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